The PRACE HPC infrastructure is made up of eight Tier-0 systems and seventeen Tier-1 systems, connected via VPN.
Tier-0 Systems
Five countries and six partners provide the following Tier-0 systems, and allow a peak up to 77 Petaflop/s.
| Country | Site (Partner) | HPC System | RPeak (Teraflop/s) |
| France | CEA (GENCI) | Joliot-Curie KNL | 2 300 |
| France | CEA (GENCI) | Joliot-Curie Rome | 12 000 |
| France | CEA (GENCI) | Joliot-Curie SKL | 6 600 |
| Germany | JUELICH (FZJ) | JUWELS Booster | 71 000 |
| Germany | JUELICH (FZJ) | JUWELS Cluster | 9 900 |
| Germany | LRZ (GCS) | SuperMUC-NG | 26 900 |
| Germany | HLRS (GCS) | HAWK | 25 200 |
| Italy | CINECA (CINECA) | Marconi100 | 20 000 |
| Spain | BSC (BSC) | MareNostrum 4 | 11 150 |
| Switzerland | CSCS (ETH) | Piz Daint | 15 988 |
Pictures of PRACE Tier-0 Systems, as further described here.
Tier-1 Systems
Twelve countries and twelve partners provide the Tier-1 systems, and allow a peak up to 16.21 Petaflop/s.
| Country | Site (Partner) | HPC System | RPeak (Teraflop/s) |
| Czech Republic | IT4I/VSB-TUO (VSB-TUO) | Anselm | 66 |
| Czech Republic | IT4I/VSB-TUO (VSB-TUO) | Salomon | 2 000 |
| Finland | CSC | Mahti | 7 060.7 |
| France | IDRIS (GENCI) | Turing | 1 258 |
| Greece | GRNET (GRNET) | ARIS | 190.8 |
| Hungary | KIFU (KIFU) | Leo | 254 |
| Hungary | KIFU (KIFU) | PHItagoras | 27 |
| Ireland | ICHEC (ICHEC) | Kay | 665 |
| Norway | UIO (Sigma2) | Abel | 178.6 |
| Poland | CYFRONET (PSNC) | Zeus (BigMem) | 61.2 |
| Poland | CYFRONET (PSNC) | Prometheus | 2 400 |
| Poland | PSNC (PSNC) | Eagle | 1 380 |
| Poland | WCSS (PSNC) | Bem | 640 |
| Slovakia | CCSAS (CCSAS) | Aurel | 128 |
| Spain | BSC (BSC) | MINOTAURO | 250.9 |
| Sweden | PDC (SNIC) | Beskow | 1 973 |
| The Netherlands | SURFsara (SURFsara) | Cartesius | 1 843 |
| United Kingdom | EPCC (EPCC) | ARCHER | 2 550.5 |
The different HPC systems are connected via a dedicated PRACE VPN.